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Thursday, 29 September 2016

Metofane

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Metofane

Methoxyflurane

Methoxyflurane is reported as an ingredient of Metofane in the following countries:

United States

International Drug Name Search

Wednesday, 28 September 2016

chlorothiazide and reserpine

Generic Name: chlorothiazide and reserpine (klor oh THYE a zide and re SER peen)

Brand Names: Diupres-250, Diupres-500

What is chlorothiazide and reserpine?

Reserpine lowers blood pressure by decreasing the amount of certain chemicals in your body. This allows your blood vessels (veins and arteries) to relax and your heart to beat more slowly and easily.

Chlorothiazide is a thiazide diuretic (water pill). It helps to lower your blood pressure and decrease edema (swelling) by increasing the amount of salt and water you lose in your urine.

Chlorothiazide and reserpine is used to lower high blood pressure.

Chlorothiazide and reserpine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about chlorothiazide and reserpine?

Stand up slowly from a sitting or lying position. Chlorothiazide and reserpine may make you feel dizzy. Do not stop taking chlorothiazide and reserpine suddenly. Even if you feel better, you need this medication to control your condition. Stopping suddenly could cause severe high blood pressure, anxiety, and other dangerous side effects.

Tell your doctor and dentist that you are taking this medication before having surgery.

Who should not take chlorothiazide and reserpine?

Do not take chlorothiazide and reserpine if you have an allergy to sulfa-based drugs such as sulfa antibiotics. You may have an allergic reaction to chlorothiazide.

You must not take chlorothiazide and reserpine if you

have peptic ulcer disease (stomach ulcers);

have ulcerative colitis;

are suffering from depression (especially if you have suicidal thoughts);

are receiving electroconvulsive shock therapy; or

are taking a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate).

Before taking this medication, tell your doctor if you have

gallstones or other stomach problems,

kidney or liver disease,

diabetes,

gout,

a collagen vascular disease such as systemic lupus erythematosus,

high cholesterol or triglyceride levels,

pancreatitis,

asthma, or

any type of heart disease.

You may require a lower dose or special monitoring during therapy with chlorothiazide and reserpine if you have any of the conditions listed above.

Chlorothiazide and reserpine is in the FDA pregnancy category C. This means that it is not known whether chlorothiazide and reserpine will harm an unborn baby. Do not take chlorothiazide and reserpine without first talking to your doctor if you are pregnant. Chlorothiazide and reserpine passes into breast milk and may harm a nursing infant. Do not take chlorothiazide and reserpine without first talking to your doctor if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects from chlorothiazide and reserpine therapy. You may require a lower dose of this medication. Chlorothiazide and reserpine has not been approved for use by children.

How should I take chlorothiazide and reserpine?

Take chlorothiazide and reserpine exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Take chlorothiazide and reserpine with food or milk if it upsets your stomach. Do not stop taking chlorothiazide and reserpine suddenly. Even if you feel better, you need this medication to control your condition. Stopping suddenly could cause severe high blood pressure, anxiety, and other dangerous side effects. Store this medication at room temperature away from moisture and heat.

See also: Chlorothiazide and reserpine dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a chlorothiazide and reserpine overdose include low blood pressure (fainting, dizziness, weakness); sleepiness; uncontrollable hand, leg, or arm movements; a slow pulse; low body temperature; diarrhea; increased urination; vomiting; and slow breathing.

What should I avoid while taking chlorothiazide and reserpine?

Avoid a diet high in salt. Too much salt will cause your body to retain water and will decrease the effects of chlorothiazide.

Use caution when arising from a sitting or lying position, especially first thing in the morning. You may become dizzy while taking chlorothiazide and reserpine and you may fall and injure yourself if you get up quickly.

Do not let yourself become overheated in hot weather or during exercise, and use caution if you have a fever. These situations increase the effects of chlorothiazide and reserpine in your body, and you may become very dizzy.

Also, chlorothiazide may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. Avoid alcohol while taking chlorothiazide and reserpine. Alcohol, which will further lower your blood pressure, will also increase the drowsiness caused by chlorothiazide and reserpine and may increase dizziness. Use caution even with small amounts of alcohol.

Do not take any over the counter cough, cold, allergy, sleep, or diet medications without first asking your doctor or pharmacist. These will interfere with your chlorothiazide and reserpine therapy.

Use caution when you are driving, operating machinery, or performing other hazardous activities until you know how chlorothiazide and reserpine affects you. If it makes you dizzy or drowsy, avoid these activities.

Tell your doctor and dentist that you are taking this medication before having surgery.

Chlorothiazide and reserpine side effects

If you experience any of the following serious side effects, stop taking chlorothiazide and reserpine and seek emergency medical attention:

an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue or face, hives);

a very irregular heartbeat;

heart failure (shortness of breath, swelling of ankles or legs, sudden weight gain of 5 pounds or more);

unusual fatigue;

abnormal bleeding or bruising;

yellow skin or eyes;

confusion;

fainting;

uncontrollable hand, arm, or leg movements;

chest pain; or

little or no urine.

Other, less serious side effects are more likely to occur. Continue to take chlorothiazide and reserpine and talk to your doctor if you experience

fatigue or drowsiness;

dizziness (avoid standing up too quickly and use caution when performing hazardous activities);

anxiety, depression, or nightmares;

diarrhea, nausea, vomiting, or an acid stomach (take chlorothiazide and reserpine with food or milk if it upsets your stomach);

abdominal pain;

stuffy nose or a dry mouth (sucking on ice chips or sugarless hard candy may relieve a dry mouth);

blurred vision;

headache;

tingling or numbness in your arms, legs, hands, or feet;

excessive urination;

muscle weakness or cramps;

increased hunger or thirst;

weight gain;

sensitivity to sunlight; or

impotence or difficulty ejaculating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Chlorothiazide and reserpine Dosing Information

Usual Adult Dose for Hypertension:

Initial dose: 1-2 tablets (chlorothiazide/reserpine 250 mg-0.125 mg) orally once or twice a day or
1 tablet (chlorothiazide/reserpine 500 mg-0.125 mg) orally once or twice a day.
Should conform to the dosages of the individual components established during titration.

What other drugs will affect chlorothiazide and reserpine?

Do not take reserpine and chlorothiazide if you are taking a monoamine oxidase inhibitor (MAOI), or if you have taken one in the last 14 days. MAOIs, used to treat depression, include isocarboxazid (Marplan), phenelzine (Nardil), and tranylcypromine (Parnate).

Before taking this medication, tell your doctor if you are taking any of the following medicines:

tricyclic antidepressants such as amitriptyline (Elavil, Endep) or doxepin (Sinequan), which may decrease the effects of reserpine and chlorothiazide;

other commonly used tricyclic antidepressants, including amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil);

digoxin (Lanoxin) or quinidine (Cardioquin, Quinidex, Quinora, Quinaglute), which will increase the risk that you will experience an irregular heartbeat when it is taken with chlorothiazide and reserpine;

barbiturates such as phenobarbital (Luminal, Solfoton), amobarbital (Amytal), and secobarbital (Seconal), which may cause extreme sleepiness or dizziness if taken with reserpine and chlorothiazide;

narcotic pain relievers such as codeine (Tylenol #3, Tylenol #4, others), propoxyphene (Darvon, Darvocet, Wygesic), oxycodone (Percodan, Percocet, Tylox), meperidine (Demerol), morphine (MS Contin, Duramorph, others), and others, which also may cause extreme sleepiness or dizziness if taken with reserpine and chlorothiazide;

steroid medications such as hydrocortisone (Hydrocortone, Cortef), prednisone (Deltasone, Orasone), prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), betamethasone (Celestone), dexamethasone (Decadron, Hexadrol), and others, which may increase the side effects of chlorothiazide;

prescription and over-the-counter cough, cold, allergy, diet, and sleeping pills, any of which may contain drugs that increase your blood pressure and heart rate and thus decrease the effects of reserpine;

the cholesterol-lowering drugs cholestyramine (Questran) and colestipol (Colestid), which may decrease the effects of chlorothiazide;

nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil), ketoprofen (Orudis, Orudis, KT, Oruvail), and naproxen (Naprosyn, Anaprox, Aleve), which may also decrease the effects of chlorothiazide;

other commonly used NSAIDs, including diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), mefenamic acid (Ponstel), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), and tolmetin (Tolectin);

oral antidiabetic drugs such as Glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase) and tolbutamide (Orinase), which may not lower your blood sugar as well during therapy with chlorothiazide and reserpine (your diabetes therapy may have to be adjusted);

lithium (Lithobid, Eskalith, others), which should not be taken with chlorothiazide because serious side effects may result; or

other drugs that also lower blood pressure, including acebutolol (Sectral), atenolol (Tenormin), bisoprolol (Zebeta), carteolol (Cartrol), labetalol (Trandate, Normodyne), propranolol (Inderal), pindolol (Visken), timolol (Blocadren), benazepril (Lotensin), enalapril (Vasotec), captopril (Capoten), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), ramipril (Altace), amlodipine (Norvasc), bepridil (Vascor), diltiazem (Cardizem, Dilacor), felodipine (Plendil), isradipine (Dynacirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), and verapamil (Calan, Veralan, Isoptin).

Drugs other than those listed here may also interact with chlorothiazide and reserpine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More chlorothiazide and reserpine resources

Chlorothiazide and reserpine Dosage
Chlorothiazide and reserpine Use in Pregnancy & Breastfeeding
Drug Images
Chlorothiazide and reserpine Drug Interactions
Chlorothiazide and reserpine Support Group
0 Reviews for Chlorothiazide and reserpine - Add your own review/rating

Compare chlorothiazide and reserpine with other medications

High Blood Pressure

Where can I get more information?

Your pharmacist has additional information about chlorothiazide and reserpine written for health professionals that you may read.

What does my medication look like?

Chlorothiazide and reserpine is available with a prescription under the brand name Diupres. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Chlorothiazide/reserpine strengths are as follows:

Diupres-250 (250 mg/ 0.125 mg)--pink, round, scored, compressed tablets

Diupres-500 (500 mg/ 0.125 mg)--pink, round, scored, compressed tablets

Tuesday, 27 September 2016

Clolar

Generic Name: Clofarabine
Class: Antineoplastic Agents
Chemical Name: 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine
Molecular Formula: C₁₀H₁₁ClFN₅O₃
CAS Number: 123318-82-1

Introduction

Antimetabolite antineoplastic agent; synthetic purine nucleoside.¹ ² ⁴ ⁵ ⁶ ⁷

Uses for Clolar

Acute Lymphocytic Leukemia

Treatment of acute lymphocytic (lymphoblastic) leukemia (ALL) refractory to or relapsed after at least 2 prior therapies in patients 1–21 years of age.¹ ² ³ ⁴ ⁵ ⁶ ⁷ Designated an orphan drug by FDA for this use.² ³

Current indication based on induction of complete responses; randomized studies showing increased survival or other clinical benefits have not been conducted to date.¹

Clolar Dosage and Administration

General

Consult specialized references for procedures for proper handling and disposal of antineoplastics.¹

Monitor respiratory status and BP during infusion, especially in patients receiving drugs that affect BP or cardiac function.¹ (See Systemic Inflammatory Response Syndrome (SIRS)/Capillary Leak Syndrome under Cautions.)

Administer IV fluids continuously throughout the 5 days of clofarabine therapy to reduce the effects of tumor lysis and other adverse effects.¹ Administer allopurinol if tumor lysis is expected to prevent hyperuricemia.¹ (See Tumor Lysis Syndrome under Cautions.)

Administration of corticosteroids (e.g., hydrocortisone 100 mg/m² on days 1–3) may prevent signs and symptoms of cytokine release or capillary leak syndrome.¹ (See Systemic Inflammatory Response Syndrome (SIRS)/Capillary Leak Syndrome under Cautions.)

Administration

Administer by IV infusion.¹

IV Infusion

Administer IV infusion over 2 hours.¹

Other drugs should not be infused through the same IV line.¹

Dilution

Dilute the commercially available injection for IV infusion (1 mg/mL) prior to administration.¹

Filter the appropriate dose through a sterile 0.2μm filter and further dilute with 5% dextrose injection or 0.9% sodium chloride injection.¹

Dosage

Dosage is based on the patient’s body surface area and is calculated using the actual body weight and height of the patient before starting each cycle.¹

Pediatric Patients

Acute Lymphocytic Leukemia

IV

1–21 years of age: 52 mg/m² by IV infusion over 2 hours daily for 5 consecutive days.¹

Repeat treatment cycle following recovery or return to baseline organ function, approximately every 2–6 weeks.¹

Discontinue infusion immediately and initiate appropriate supportive measures if early manifestations of cytokine release or capillary leak syndrome occur.¹ Consider reinstitution of therapy, generally at a lower dosage, if patient is stable and organ function has returned to baseline levels.¹ (See Systemic Inflammatory Response Syndrome (SIRS)/Capillary Leak Syndrome under Cautions.)

Discontinue infusion immediately if substantial increases in serum creatinine or bilirubin concentrations occur.¹ Consider reinstitution of therapy, generally at a lower dosage, once the patient is stable and organ function has returned to baseline levels.¹

Discontinue infusion immediately if hypotension develops.¹ Consider reinstitution of therapy at a lower dosage if hypotension was transient and resolved without pharmacologic intervention.¹

Special Populations

No special population dosage recommendations at this time.¹

Cautions for Clolar

Contraindications

No known contraindications to use of clofarabine;¹ use with caution in patients with known hypersensitivity to the drug or any ingredient in the formulation.⁸

Warnings/Precautions

Warnings

Administer only under supervision of clinicians qualified in use of cytotoxic therapy.¹

Hematologic Effects and Infectious Complications

Anticipate bone marrow suppression (usually reversible and dose dependent) with use.¹

Severe bone marrow suppression (neutropenia, anemia, thrombocytopenia) reported.¹

Increased risk of developing infectious complications, including severe sepsis and opportunistic infections.¹

Tumor Lysis Syndrome

Monitor for signs and symptoms of tumor lysis syndrome.¹

Use appropriate measures (e.g., hydration, allopurinol) to prevent hyperuricemia.¹

Systemic Inflammatory Response Syndrome (SIRS)/Capillary Leak Syndrome

Signs and symptoms of cytokine release (i.e., tachypnea, tachycardia, hypotension, pulmonary edema) reported.¹

Rapid onset of respiratory distress, hypotension, capillary leak (e.g., pleural and pericardial effusions), and multiorgan failure reported.¹

Monitor closely and intervene early by discontinuance of the drug and supportive measures (e.g., corticosteroids, diuretics, and/or albumin).¹

Development of SIRS or capillary leak syndrome may be fatal.¹ (See Dosage under Dosage and Administration.)

Fetal/Neonatal Morbidity and Mortality

May cause fetal harm; teratogenicity demonstrated in animals.¹

Avoid pregnancy during therapy.¹ If used during pregnancy, apprise of potential fetal hazard.¹

General Precautions

Adequate Patient Monitoring

Perform CBC, including platelet counts at regular intervals; more frequently in patients who develop cytopenias.¹

Monitor hepatic and renal function prior to therapy and throughout the 5 days of clofarabine administration.¹

Specific Populations

Pregnancy

Category D. (See Fetal/Neonatal Morbidity and Mortality under Cautions.)¹

Lactation

Not known whether clofarabine or its metabolites are distributed into milk.¹

Discontinue nursing because of potential risk to nursing infants.¹

Pediatric Use

Safety and efficacy established for treatment of relapsed or refractory ALL in patients 1–21 years of age.¹

Evaluated in a limited number of children with refractory acute myeloid leukemia (AML)†.² ⁴ ⁵ ⁶ ⁷

Adult Use

Safety and efficacy not established in adults >21 years of age.¹

Dosage of 40 mg/m² (given by IV infusion over 1–2 hours) daily for 5 days every 28 days was used in a phase II clinical trial in adults with relapsed or refractory hematologic malignancies.¹ ² ⁶

Hepatic Impairment

[64] Not studied in patients with hepatic impairment; use with caution.¹

[64] If increases in bilirubin concentrations occur, withhold drug until hepatic function returns to baseline.¹ Dosage adjustment may be considered.¹

Renal Impairment

Not studied in patients with renal impairment; use with caution.¹

If substantial increases in serum creatinine concentrations occur, withhold drug until renal function returns to baseline.¹ Dosage adjustment may be considered.¹

Common Adverse Effects

Nausea, vomiting, diarrhea, anemia, leukopenia, thrombocytopenia, neutropenia (including febrile neutropenia), infections.¹

Interactions for Clolar

No formal drug interaction studies to date.¹

Interaction with drugs that induce or inhibit CYP 450 isoenzymes not expected.¹

Nephrotoxic Drugs

Avoid concomitant use with nephrotoxic drugs throughout the 5 days of clofarabine administration because clofarabine is eliminated by kidneys.¹

Hepatotoxic Drugs

Avoid concomitant use with hepatotoxic drugs because clofarabine may cause hepatotoxicity.¹

Clolar Pharmacokinetics

Distribution

Plasma Protein Binding

47% (mainly albumin) in pediatric patients.¹

Elimination

Metabolism

Metabolized to active 5-triphosphate metabolite.¹ ⁵

Undergoes limited hepatic metabolism (0.2%) in pediatric patients.¹

Elimination Route

Excreted in urine (49–60%) as unchanged drug in pediatric patients.¹

Half-life

Estimated terminal half-life about 5.2 hours in pediatric patients.¹

Special Populations

Pharmacokinetics not studied in patients with renal or hepatic impairment.¹

Stability

Storage

Parenteral

Injection for IV infusion

25°C (may be exposed to 15–30°C).¹

Store diluted solutions at room temperature; discard after 24 hours.¹

ActionsActions

Inhibits DNA synthesis, inhibits ribonucleoside reductase, and has direct effects on mitochondria; these effects lead to depletion of intracellular deoxynucleotide triphosphate pools, inhibition of elongation of DNA strands during synthesis, and release of proapoptotic mitochondrial factors in both actively dividing and quiescent tumor cells.¹ ² ⁶

Advice to Patients

Advise patients about risk of dehydration secondary to vomiting and diarrhea.¹

Importance of advising patients regarding appropriate measures to avoid dehydration.¹

Advise patients to notify clinician immediately if symptoms of hypotension (e.g., dizziness, lightheadedness, fainting spell) or decreased urine output occurs.¹

Importance of monitoring blood cell counts, renal and hepatic function.¹

Necessity of advising women to use an effective method of contraception and to avoid breast-feeding while receiving clofarabine therapy.¹

Importance of women informing a clinician immediately if they are or plan to become pregnant or plan to breast-feed.¹ Advise pregnant women of risk to the fetus.¹

Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as any concomitant illnesses.¹

Importance of informing patients of other important precautionary information.¹ (See Cautions.)

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Clofarabine
Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Parenteral	For injection, for IV infusion	1 mg/mL (20 mg)	Clolar	Genzyme

Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions May 2006. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.

† Use is not currently included in the labeling approved by the US Food and Drug Administration.

References

1. Genzyme Corporation. Clolar (clofarabine) for intravenous infusion prescribing information. Cambridge, MA; 2005.

2. Anon. Clofarabine. Drugs R &D. 2004; 5:213-7.

3. Food and Drug Administration. Orphan designations pursuant to Section 526 of the Federal Food and Cosmetic Act as amended by the Orphan Drug Act (P.L. 97 414). Rockville, MD. From FDA website (). Accessed 2005 Jan 25.

4. Jeha S, Razzouk B, Gaynon P et al. Phase II trials of clofarabine in pediatric acute leukemia. Presented at the American Society of Clinical Oncologists Annual Meeting 2005. From the ASCO website (). Abstract No. 6588. Accessed 2005 Jun 21.

5. Jeha S, Gandhi V, Chan KW et al. Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia. Blood. 2004;103:784-9.

6. Faderl S, Gandhi V, Keating MJ et al. The role of clofarabine in hematologic and solid malignancies–development of a next-generation nucleoside analog. Cancer. 2005; 103:1985-95. [IDIS 533862] [PubMed 15803490]

7. Jeha S, Razzouk BI, Rytting ME et al. Phase II trials of clofarabine in relapsed or refractory pediatric leukemia. Presented at the American Society of Hematology Annual Meeting 2004. From the ASH website (). Abstract No. 684. Accessed 2005 Jun 30.

8. Genzyme Corporation, Cambridge, MA: personal communication.

More Clolar resources

Clolar Side Effects (in more detail)
Clolar Use in Pregnancy & Breastfeeding
Clolar Drug Interactions
Clolar Support Group
0 Reviews for Clolar - Add your own review/rating

Clolar Prescribing Information (FDA)

Clolar Consumer Overview

Clolar Advanced Consumer (Micromedex) - Includes Dosage Information

Clolar MedFacts Consumer Leaflet (Wolters Kluwer)

Clofarabine Professional Patient Advice (Wolters Kluwer)

Compare Clolar with other medications

Acute Lymphoblastic Leukemia

Monday, 26 September 2016

Furosemid Kabi

Furosemid Kabi may be available in the countries listed below.

Ingredient matches for Furosemid Kabi

Furosemide

Furosemide is reported as an ingredient of Furosemid Kabi in the following countries:

Slovakia

International Drug Name Search

chlophedianol, guaifenesin, and phenylephrine

Generic Name: chlophedianol, guaifenesin, and phenylephrine (KLOE fe DYE a nol, gwye FEN e sin, and FEN il EFF rin)

Brand Names: Donatussin

What is chlophedianol, guaifenesin, and phenylephrine?

Chlophedianol is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of chlophedianol, guaifenesin, and phenylephrine is used to treat stuffy nose, cough, chest congestion, and sinus congestion caused by allergies, the common cold, or the flu.

Chlophedianol, guaifenesin, and phenylephrine will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlophedianol, guaifenesin, and phenylephrine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about chlophedianol, guaifenesin, and phenylephrine?

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use cough or cold medicine if you have untreated or uncontrolled diseases such as high blood pressure, heart disease, coronary artery disease, or a thyroid disorder. Do not use a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

What should I discuss with my healthcare provider before taking chlophedianol, guaifenesin, and phenylephrine?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Do not use cough or cold medicine if you have untreated or uncontrolled diseases such as high blood pressure, heart disease, coronary artery disease, or a thyroid disorder.

To make sure you can safely use this medicine, tell your doctor if you have any of these other conditions:

diabetes;

epilepsy or other seizure disorder;

cough with mucus, or cough caused by emphysema, or chronic bronchitis;

enlarged prostate or urination problems; or

pheochromocytoma (an adrenal gland tumor).

It is not known whether chlophedianol, guaifenesin, and phenylephrine will harm an unborn baby. Do not use cough or cold medicine without telling your doctor if you are pregnant or plan to become pregnant while using the medicine. Chlophedianol, guaifenesin, and phenylephrine may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use cough or cold medicine without telling your doctor if you are breast-feeding a baby.

How should I take chlophedianol, guaifenesin, and phenylephrine?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

Do not take for longer than 7 days in a row. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache or skin rash.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken a cough or cold medicine within the past few days. Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Since cough or cold medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking chlophedianol, guaifenesin, and phenylephrine?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of chlophedianol, guaifenesin, and phenylephrine. Ask a doctor or pharmacist before using any other cold, allergy, or cough medicine. Antitussives, expectorants, and decongestants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antitussive, expectorant, or decongestant.

Avoid taking this medication if you also take diet pills, caffeine pills, or other stimulants (such as ADHD medications). Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Chlophedianol, guaifenesin, and phenylephrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using chlophedianol, guaifenesin, and phenylephrine and call your doctor at once if you have a serious side effect such as:

fast, slow, or uneven heart rate;

severe dizziness or anxiety, feeling like you might pass out;

mood changes, hallucinations;

severe headache;

tremor, seizure (convulsions);

fever; or

dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, uneven heartbeats, seizure).

Less serious side effects may include:

mild dizziness or drowsiness;

mild headache;

diarrhea, constipation, nausea, upset stomach;

sleep problems (insomnia); or

feeling nervous or restless.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Chlophedianol, guaifenesin, and phenylephrine Dosing Information

Usual Adult Dose for Cough and Nasal Congestion:

Chlophedianol/guaiFENesin/phenylephrine 12.5 mg-120 mg-5 mg/5 mL oral liquid:
10 mL orally every 6 to 8 hours not to exceed 40 mL daily.

Usual Pediatric Dose for Cough and Nasal Congestion:

Chlophedianol/guaiFENesin/phenylephrine 12.5 mg-120 mg-5 mg/5 mL oral liquid:
2 to 5 years: 2.5 mL orally every 6 to 8 hours not to exceed 10 mL daily.
6 to 11 years: 5 mL orally every 6 to 8 hours not to exceed 20 mL daily.
12 years or older: 10 mL orally every 6 to 8 hours not to exceed 40 mL daily.

What other drugs will affect chlophedianol, guaifenesin, and phenylephrine?

Before using chlophedianol, guaifenesin, and phenylephrine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by chlophedianol or guaifenesin.

There may be other drugs that can interact with chlophedianol, guaifenesin, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More chlophedianol, guaifenesin, and phenylephrine resources

Chlophedianol, guaifenesin, and phenylephrine Side Effects (in more detail)
Chlophedianol, guaifenesin, and phenylephrine Drug Interactions
Chlophedianol, guaifenesin, and phenylephrine Support Group
0 Reviews for Chlophedianol, guaifenesin, and phenylephrine - Add your own review/rating

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Cough and Nasal Congestion

Where can I get more information?

Your pharmacist can provide more information about chlophedianol, guaifenesin, and phenylephrine.

See also: chlophedianol, guaifenesin, and phenylephrine side effects (in more detail)

Friday, 23 September 2016

Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid

Pronunciation: klor-fen-EER-a-meen/hye-droe-KOE-done/sue-do-eh-FED-rin
Generic Name: Chlorpheniramine/Hydrocodone/Pseudoephedrine
Brand Name: Generic only. No brands available.

Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid is a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex, which reduces a dry cough.

Do NOT use Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid if:

you are allergic to any ingredient in Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid or any other codeine- or morphine-related medicine (eg, codeine)

you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems

you are unable to urinate or are having an asthma attack

you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid:

Some medical conditions may interact with Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a fast, slow, or irregular heartbeat, heart blood vessel problems, or other heart problems

if you have a history of adrenal gland problems (eg, adrenal gland tumor); high blood pressure; diabetes; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; or an overactive thyroid

if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus

if you have or recently have had any head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures

if you have a history of stomach problems (eg, ulcers), bowel problems (eg, chronic inflammation or ulceration of the bowel), or gallbladder problems (eg, gallstones), or if you have had recent abdominal surgery

if you have a history of alcohol or substance abuse or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid's side effects

Cimetidine, digoxin, droxidopa, or sodium oxybate (GHB) because the risk of severe drowsiness, breathing problems, seizures, irregular heartbeat, or heart attack may be increased

Naltrexone because it may decrease Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid's effectiveness

Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid

Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid:

Use Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid by mouth with or without food.

Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

If you miss a dose of Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid.

Important safety information:

Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Do not take diet or appetite control medicines while you take Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid without checking with your doctor.

Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.

Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid for a few days before the tests.

Tell your doctor or dentist that you take Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid before you receive any medical or dental care, emergency care, or surgery.

Use Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid with caution in the ELDERLY; they may be more sensitive to its effects.

Caution is advised when using Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid in CHILDREN; they may be more sensitive to its effects.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid while you are pregnant. It is not known if Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid is found in breast milk. Do not breast-feed while taking Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid.

When used for long periods of time or at high doses, Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid stops working well. Do not take more than prescribed.

When used for longer than a few weeks or at high doses, some people develop a need to continue taking Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid. This is known as DEPENDENCE or addiction.

If you suddenly stop taking Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; trouble sleeping.

Possible side effects of Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Chlorpheniramine/Hydrocodone/Pseudoephedrine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid:

Store Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid out of the reach of children and away from pets.

General information:

If you have any questions about Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid, please talk with your doctor, pharmacist, or other health care provider.

Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Chlorpheniramine/Hydrocodone/Pseudoephedrine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More Chlorpheniramine/Hydrocodone/Pseudoephedrine resources

Chlorpheniramine/Hydrocodone/Pseudoephedrine Side Effects (in more detail)
Chlorpheniramine/Hydrocodone/Pseudoephedrine Use in Pregnancy & Breastfeeding
Chlorpheniramine/Hydrocodone/Pseudoephedrine Drug Interactions
Chlorpheniramine/Hydrocodone/Pseudoephedrine Support Group
4 Reviews for Chlorpheniramine/Hydrocodone/Pseudoephedrine - Add your own review/rating

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Cough and Nasal Congestion

carbetapentane, chlorpheniramine, ephedrine, and phenylephrine

Generic Name: carbetapentane, chlorpheniramine, ephedrine, and phenylephrine (kar BET a PEN tane, klor fen EER a meen, ee FED rin, and FEN il EFF rin)

Brand names: Rentamine, Rynatuss, Tuss Tan, ...show all 10 brand names.

What is carbetapentane, chlorpheniramine, ephedrine, and phenylephrine?

Chlorpheniramine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Chlorpheniramine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.

Carbetapentane is a cough suppressant. It suppresses an area in the brain that causes coughing.

Ephedrine and phenylephrine are decongestants. They constrict blood vessels (veins and arteries). This reduces the blood flow and allows nasal passages to open up.

Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine is used to treat nasal congestion, sinusitis (inflammation of the sinuses), and coughs associated with allergies, hay fever, and the common cold.

Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about carbetapentane, chlorpheniramine, ephedrine, and phenylephrine?

Use caution when driving, operating machinery, or performing other hazardous activities. Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking carbetapentane, chlorpheniramine, ephedrine, and phenylephrine.

Do not take more of this medication than is recommended. If your symptoms do not improve or if they worsen, talk to your doctor.

Who should not take carbetapentane, chlorpheniramine, ephedrine, and phenylephrine?

Do not take carbetapentane, chlorpheniramine, ephedrine, and phenylephrine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

kidney disease,

liver disease,

diabetes,

glaucoma,

heart disease or high blood pressure,

thyroid disease,

emphysema or chronic bronchitis, or

difficulty urinating or have an enlarged prostate.

You may not be able to take carbetapentane, chlorpheniramine, ephedrine, and phenylephrine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether carbetapentane, chlorpheniramine, ephedrine, and phenylephrine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine passes into breast milk and may harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects from carbetapentane, chlorpheniramine, ephedrine, and phenylephrine. You may require a lower dose of this medication. Read the package label for directions or consult your doctor or pharmacist before treating a child with this medication. Children are more susceptible than adults to the effects of medicines and may have unusual reactions.

How should I take carbetapentane, chlorpheniramine, ephedrine, and phenylephrine?

Take carbetapentane, chlorpheniramine, ephedrine, and phenylephrine exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. To ensure that you get a correct dose, measure the liquid form of carbetapentane, chlorpheniramine, ephedrine, and phenylephrine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Do not take more of this medication than is recommended. An overdose of this medication can cause serious harm.

Do not take carbetapentane, chlorpheniramine, ephedrine, and phenylephrine for longer than 7 days in a row. If your symptoms do not improve, if they get worse, or if you have a fever, talk to your doctor.

Store carbetapentane, chlorpheniramine, ephedrine, and phenylephrine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a carbetapentane, chlorpheniramine, ephedrine, and phenylephrine overdose include dry mouth, large pupils, flushing, nausea and vomiting, hyperactivity, and hallucinations.

What should I avoid while taking carbetapentane, chlorpheniramine, ephedrine, and phenylephrine?

Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if carbetapentane, chlorpheniramine, ephedrine, and phenylephrine is taken with any of these medications.

Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine side effects

Serious side effects are unlikely to occur. Stop taking carbetapentane, chlorpheniramine, ephedrine, and phenylephrine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take carbetapentane, chlorpheniramine, ephedrine, and phenylephrine and talk to your doctor or try another similar medication if you experience

dryness of the eyes, nose, and mouth;

drowsiness or dizziness;

blurred vision;

difficulty urinating; or

excitation in children.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect carbetapentane, chlorpheniramine, ephedrine, and phenylephrine?

Do not take other over-the-counter cough, cold, allergy, diet, pain, or sleep medications while taking carbetapentane, chlorpheniramine, ephedrine, and phenylephrine without first talking to your pharmacist or doctor. Other medications may also contain carbetapentane, chlorpheniramine, ephedrine, phenylephrine, or other similar drugs, and you may accidentally take too much of these medicines.

Drugs other than those listed here may also interact with carbetapentane, chlorpheniramine, ephedrine, and phenylephrine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More carbetapentane, chlorpheniramine, ephedrine, and phenylephrine resources

Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine Side Effects (in more detail)
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Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine Support Group
0 Reviews for Carbetapentane, chlorpheniramine, ephedrine, and phenylephrine - Add your own review/rating

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Cold Symptoms
Nasal Congestion
Sinus Symptoms

Where can I get more information?

Your pharmacist can provide more information about carbetapentane, chlorpheniramine, ephedrine, and phenylephrine.

See also: carbetapentane, chlorpheniramine, ephedrine, and phenylephrine side effects (in more detail)